BMJ Open Ophthalmology (Aug 2024)

Relation between a history of glaucoma and subjective happiness: the JPHC-Next study

  • Isao Muraki,
  • Kazumasa Yamagishi,
  • Kazuno Negishi,
  • Norie Sawada,
  • Shoichiro Tsugane,
  • Manami Inoue,
  • Taiki Yamaji,
  • Motoki Iwasaki,
  • Ryutaro Yamanishi,
  • Kenya Yuki,
  • Isao Saito,
  • Kiyoshi Aoyagi,
  • Kozo Tanno,
  • Kazuhiko Arima,
  • Miki Uchino,
  • Nobufumi Yasuda,
  • Erisa Yotsukura,
  • Akiko Hanyuda,
  • Tadahiro Kato

DOI
https://doi.org/10.1136/bmjophth-2023-001553
Journal volume & issue
Vol. 9, no. 1

Abstract

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Objective This population-based, cross-sectional study was performed to investigate the relationship between a history of glaucoma and subjective happiness.Methods and analysis We conducted a cross-sectional questionnaire-based survey of 92 397 Japanese men and women aged 40–74 who participated in the Japan Public Health Center-based Prospective Study for the Next Generation study. A multivariable logistic regression model was used to estimate the ORs of glaucoma associated with subjective happiness and their two-sided 95% CIs.Results Among 40 727 men and 51 670 women, 1733 participants (635 men, 1098 women) had a history of glaucoma. The odds of unhappiness in male participants with a history of glaucoma were higher (OR 1.26; 95% CI 1.05 to 1.51) than in female participants (OR 1.05; 95% CI 0.90 to 1.23). In a subgroup analysis stratified by age, among participants with a history of glaucoma, males in the younger group (40–59 years) showed the most robust association with unhappiness (OR 1.40; 95% CI 1.04 to 1.88).Conclusions These findings suggest that a history of glaucoma is related with subjective unhappiness, especially in men.