Nature Communications (May 2020)

Long-term alterations in brain and behavior after postnatal Zika virus infection in infant macaques

  • Jessica Raper,
  • Zsofia Kovacs-Balint,
  • Maud Mavigner,
  • Sanjeev Gumber,
  • Mark W. Burke,
  • Jakob Habib,
  • Cameron Mattingly,
  • Damien Fair,
  • Eric Earl,
  • Eric Feczko,
  • Martin Styner,
  • Sherrie M. Jean,
  • Joyce K. Cohen,
  • Mehul S. Suthar,
  • Mar M. Sanchez,
  • Maria C. Alvarado,
  • Ann Chahroudi

DOI
https://doi.org/10.1038/s41467-020-16320-7
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 12

Abstract

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The consequences of postnatal Zika infection are not fully understood. Here, the authors show that postnatal Zika infection in infant rhesus macaques alters neurodevelopment resulting in social, cognitive and motor impairments, as well as structural and functional changes in the brain.