The Ino80 complex mediates epigenetic centromere propagation via active removal of histone H3

Eun Shik Choi; Youngseo Cheon; Keunsoo Kang; Daeyoup Lee

doi:10.1038/s41467-017-00704-3

Nature Communications (Sep 2017)

The Ino80 complex mediates epigenetic centromere propagation via active removal of histone H3

Eun Shik Choi,
Youngseo Cheon,
Keunsoo Kang,
Daeyoup Lee

Affiliations

Eun Shik Choi: Department of Biological Sciences, Korea Advanced Institute of Science and Technology
Youngseo Cheon: Department of Biological Sciences, Korea Advanced Institute of Science and Technology
Keunsoo Kang: Department of Microbiology, Dankook University
Daeyoup Lee: Department of Biological Sciences, Korea Advanced Institute of Science and Technology

DOI: https://doi.org/10.1038/s41467-017-00704-3
Journal volume & issue: Vol. 8, no. 1
pp. 1 – 10

Abstract

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The histone variant CENP-A marks active centromeres and replaces H3 at centromeres through a poorly understood mechanism. Here, the authors provide evidence that the chromatin remodeller Ino80 promotes CENP-A chromatin assembly at the centromere in fission yeast.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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