The association of aberrant folylpolyglutamate synthetase splicing with ex vivo methotrexate resistance and clinical outcome in childhood acute lymphoblastic leukemia
Anna Wojtuszkiewicz,
Yehuda G. Assaraf,
Mirthe Hoekstra,
Rocco Sciarrillo,
Gerrit Jansen,
Godefridus J. Peters,
Rob Pieters,
Edwin Sonneveld,
Gabriele Escherich,
Gertjan J.L. Kaspers,
Jacqueline Cloos
Affiliations
Anna Wojtuszkiewicz
Dept of Pediatric Oncology/Hematology, VU University Medical Center, Amsterdam, The Netherlands;Dept. of Hematology, VU University Medical Center, Amsterdam, The Netherlands
Yehuda G. Assaraf
Dept. of Biology, Technion-Israel Institute of Technology, Haifa, Israel
Mirthe Hoekstra
Dept of Pediatric Oncology/Hematology, VU University Medical Center, Amsterdam, The Netherlands
Rocco Sciarrillo
Dept of Pediatric Oncology/Hematology, VU University Medical Center, Amsterdam, The Netherlands;Dept. of Hematology, VU University Medical Center, Amsterdam, The Netherlands;Dept. of Medical Oncology, VU University Medical Center, Amsterdam, The Netherlands
Gerrit Jansen
Dept. of Rheumatology, VU University Medical Center, Amsterdam, The Netherlands
Godefridus J. Peters
Dept. of Medical Oncology, VU University Medical Center, Amsterdam, The Netherlands
Rob Pieters
Dutch Childhood Oncology Group (DCOG), The Hague, The Netherlands;Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands
Edwin Sonneveld
Dutch Childhood Oncology Group (DCOG), The Hague, The Netherlands
Gabriele Escherich
Clinic of Pediatric Hematology/Oncology, University Medical Center Eppendorf, Hamburg, Germany
Gertjan J.L. Kaspers
Dept of Pediatric Oncology/Hematology, VU University Medical Center, Amsterdam, The Netherlands
Jacqueline Cloos
Dept of Pediatric Oncology/Hematology, VU University Medical Center, Amsterdam, The Netherlands;Dept. of Hematology, VU University Medical Center, Amsterdam, The Netherlands