Communications Biology (May 2022)
Combining genomic and epidemiological data to compare the transmissibility of SARS-CoV-2 variants Alpha and Iota
- Mary E. Petrone,
- Jessica E. Rothman,
- Mallery I. Breban,
- Isabel M. Ott,
- Alexis Russell,
- Erica Lasek-Nesselquist,
- Hamada Badr,
- Kevin Kelly,
- Greg Omerza,
- Nicholas Renzette,
- Anne E. Watkins,
- Chaney C. Kalinich,
- Tara Alpert,
- Anderson F. Brito,
- Rebecca Earnest,
- Irina R. Tikhonova,
- Christopher Castaldi,
- John P. Kelly,
- Matthew Shudt,
- Jonathan Plitnick,
- Erasmus Schneider,
- Steven Murphy,
- Caleb Neal,
- Eva Laszlo,
- Ahmad Altajar,
- Claire Pearson,
- Anthony Muyombwe,
- Randy Downing,
- Jafar Razeq,
- Linda Niccolai,
- Madeline S. Wilson,
- Margaret L. Anderson,
- Jianhui Wang,
- Chen Liu,
- Pei Hui,
- Shrikant Mane,
- Bradford P. Taylor,
- William P. Hanage,
- Marie L. Landry,
- David R. Peaper,
- Kaya Bilguvar,
- Joseph R. Fauver,
- Chantal B. F. Vogels,
- Lauren M. Gardner,
- Virginia E. Pitzer,
- Kirsten St. George,
- Mark D. Adams,
- Nathan D. Grubaugh
Affiliations
- Mary E. Petrone
- Department of Epidemiology of Microbial Diseases, Yale School of Public Health
- Jessica E. Rothman
- Department of Epidemiology of Microbial Diseases, Yale School of Public Health
- Mallery I. Breban
- Department of Epidemiology of Microbial Diseases, Yale School of Public Health
- Isabel M. Ott
- Department of Epidemiology of Microbial Diseases, Yale School of Public Health
- Alexis Russell
- Wadsworth Center, New York State Department of Health
- Erica Lasek-Nesselquist
- Wadsworth Center, New York State Department of Health
- Hamada Badr
- Department of Civil and Systems Engineering, Johns Hopkins University
- Kevin Kelly
- The Jackson Laboratory for Genomic Medicine
- Greg Omerza
- The Jackson Laboratory for Genomic Medicine
- Nicholas Renzette
- The Jackson Laboratory for Genomic Medicine
- Anne E. Watkins
- Department of Epidemiology of Microbial Diseases, Yale School of Public Health
- Chaney C. Kalinich
- Department of Epidemiology of Microbial Diseases, Yale School of Public Health
- Tara Alpert
- Department of Epidemiology of Microbial Diseases, Yale School of Public Health
- Anderson F. Brito
- Department of Epidemiology of Microbial Diseases, Yale School of Public Health
- Rebecca Earnest
- Department of Epidemiology of Microbial Diseases, Yale School of Public Health
- Irina R. Tikhonova
- Yale Center for Genome Analysis, Yale University
- Christopher Castaldi
- Yale Center for Genome Analysis, Yale University
- John P. Kelly
- Wadsworth Center, New York State Department of Health
- Matthew Shudt
- Wadsworth Center, New York State Department of Health
- Jonathan Plitnick
- Wadsworth Center, New York State Department of Health
- Erasmus Schneider
- Wadsworth Center, New York State Department of Health
- Steven Murphy
- Murphy Medical Associates
- Caleb Neal
- Murphy Medical Associates
- Eva Laszlo
- Murphy Medical Associates
- Ahmad Altajar
- Murphy Medical Associates
- Claire Pearson
- Connecticut State Department of Public Health
- Anthony Muyombwe
- Connecticut State Department of Public Health
- Randy Downing
- Connecticut State Department of Public Health
- Jafar Razeq
- Connecticut State Department of Public Health
- Linda Niccolai
- Department of Epidemiology of Microbial Diseases, Yale School of Public Health
- Madeline S. Wilson
- Yale Health Center, Yale University
- Margaret L. Anderson
- Department of Epidemiology of Microbial Diseases, Yale School of Public Health
- Jianhui Wang
- Department of Pathology, Yale University School of Medicine
- Chen Liu
- Department of Pathology, Yale University School of Medicine
- Pei Hui
- Department of Pathology, Yale University School of Medicine
- Shrikant Mane
- Yale Center for Genome Analysis, Yale University
- Bradford P. Taylor
- Center for Communicable Disease Dynamics, Department of Epidemiology, Harvard T. H. Chan School of Public Health
- William P. Hanage
- Center for Communicable Disease Dynamics, Department of Epidemiology, Harvard T. H. Chan School of Public Health
- Marie L. Landry
- Departments of Laboratory Medicine and Medicine, Yale University School of Medicine
- David R. Peaper
- Departments of Laboratory Medicine and Medicine, Yale University School of Medicine
- Kaya Bilguvar
- Yale Center for Genome Analysis, Yale University
- Joseph R. Fauver
- Department of Epidemiology of Microbial Diseases, Yale School of Public Health
- Chantal B. F. Vogels
- Department of Epidemiology of Microbial Diseases, Yale School of Public Health
- Lauren M. Gardner
- Department of Civil and Systems Engineering, Johns Hopkins University
- Virginia E. Pitzer
- Department of Epidemiology of Microbial Diseases, Yale School of Public Health
- Kirsten St. George
- Wadsworth Center, New York State Department of Health
- Mark D. Adams
- The Jackson Laboratory for Genomic Medicine
- Nathan D. Grubaugh
- Department of Epidemiology of Microbial Diseases, Yale School of Public Health
- DOI
- https://doi.org/10.1038/s42003-022-03347-3
- Journal volume & issue
-
Vol. 5,
no. 1
pp. 1 – 10
Abstract
The Alpha and Iota SARS-CoV-2 variants exhibit up to 50% greater transmissibility compared to other circulating variants in Connecticut in early 2021.