Comparison of the Effect of MI Varnish (Fluoride Varnish Containing Amorphous Casein Phosphopeptide Calcium Sulfate) and V Varnish (Fluoride Varnish Containing Tricalcium Phosphate and Xylitol) on the Fluoride Uptake of Primary Tooth Enamel

Abstract

Background: Identifying fluoride combinations that result in maximum enamel uptake and greater resistance to cariogenic factors is a key concern in preventive dentistry. Among topical fluoride applications, fluoride varnishes are known to be highly effective in preventing and controlling caries, particularly in primary teeth. This study aimed to compare the effect of two types of sodium fluoride varnishes, MI Varnish (containing amorphous casein phosphopeptide calcium sulfate) and V Varnish (containing tricalcium phosphate and xylitol), on fluoride uptake in primary tooth enamel.Methods and Materials: This in vitro study included 34 extracted primary molars. Each crown was sectioned at the cementoenamel junction (CEJ) and divided into buccal and lingual halves. The samples were randomly assigned to two groups: either the V or the MI varnish group. The enamel surface of the specimen was coated with one of the varnishes. After 4 minutes, the surfaces were rinsed with saline. The fluoride and calcium contents were measured using potentiometry and spectrophotometry, respectively. Data were analyzed using SPSS version 20 and Student T-test was used to compare the amount of fluoride and calcium in the two study groups. P-value<0.05 was considered statistically significant. Results: Enamel fluoride uptake in the MI Varnish group was significantly greater compared to the V Varnish group (P=0.018). Although the calcium concentration was slightly higher in the MI Varnish group, the difference was not statistically significant (P = 0.327).Conclusion: MI Varnish appears to be more effective than V Varnish in enhancing fluoride uptake into the enamel of primary teeth, suggesting a potential advantage for caries prevention in pediatric dental care.

Keywords

• calcium compounds
• deciduous tooth
• dental enamel
• fluoride varnishes