Nano-Micro Letters (Aug 2024)

Advances in Polysaccharide-Based Microneedle Systems for the Treatment of Ocular Diseases

  • Qingdong Bao,
  • Xiaoting Zhang,
  • Zhankun Hao,
  • Qinghua Li,
  • Fan Wu,
  • Kaiyuan Wang,
  • Yang Li,
  • Wenlong Li,
  • Hua Gao

DOI
https://doi.org/10.1007/s40820-024-01477-3
Journal volume & issue
Vol. 16, no. 1
pp. 1 – 52

Abstract

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Highlights Polysaccharide-based microneedles are novel and emerging tools for ocular drug delivery and the research on the diagnosis and treatment of eye diseases is advancing at a fast pace. Microneedle devices constructed from polysaccharide molecules derived from ocular tissue have the potential to significantly enhance the efficiency of clinical treatments and improve patient compliance with therapeutic regimens. Guided by our vast clinical experience, this is the first review collates the cutting-edge scientific findings from the interdisciplinary field combining natural macromolecules and ophthalmology.

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