APOE3 AND APOE4 HIPSC-DERIVED ASTROCYTES DIFFERENTIALLY CONTRIBUTE TO ALZHEIMER’S PATHOLOGY IN CHIMERIC MICE

• Joan Cruz-Sesé,
• María Alfonso-Triguero,
• Jon Olano-Bringas,
• Leire Ruiz,
• Nuria Galbis,
• Pranav Preman,
• An Snellinx,
• Julia Tcw,
• Elena Alberdi,
• Alison Goate,
• Bart De Strooper,
• Amaia Mendiguren Arranz

Affiliations

Joan Cruz-Sesé

University of the Basque Country (UPV/EHU), Neurosciences, Leioa, Spain; Achucarro Basque Center for Neuroscience, Neurosciences, Leioa, Spain

María Alfonso-Triguero

University of the Basque Country (UPV/EHU), Neurosciences, Leioa, Spain; Achucarro Basque Center for Neuroscience, Neurosciences, Leioa, Spain

Jon Olano-Bringas

Achucarro Basque Center for Neuroscience, Neurosciences, Leioa, Spain

Leire Ruiz

Achucarro Basque Center for Neuroscience, Neurosciences, Leioa, Spain

Nuria Galbis

University of the Basque Country (UPV/EHU), Neurosciences, Leioa, Spain; Achucarro Basque Center for Neuroscience, Neurosciences, Leioa, Spain

Pranav Preman

VIB Center for Brain & Disease Research, Neurosciences, Leuven, Belgium; Laboratory for the Research of Neurodegenerative Diseases,Leuven Brain Institute (LBI), Neurosciences, Leuven, Belgium

An Snellinx

VIB Center for Brain & Disease Research, Neurosciences, Leuven, Belgium; Laboratory for the Research of Neurodegenerative Diseases,Leuven Brain Institute (LBI), Neurosciences, Leuven, Belgium

Julia Tcw

Boston University School of Medicine, Neurosciences, Boston, United States of America

Elena Alberdi

University of the Basque Country (UPV/EHU), Neurosciences, Leioa, Spain; Achucarro Basque Center for Neuroscience, Neurosciences, Leioa, Spain

Alison Goate

Ronald M. Loeb Center for Alzheimer's disease, Neurosciences, New York, United States of America

Bart De Strooper

VIB Center for Brain & Disease Research, Neurosciences, Leuven, Belgium; Laboratory for the Research of Neurodegenerative Diseases,Leuven Brain Institute (LBI), Neurosciences, Leuven, Belgium; Dementia Research Institute, University College London, Neurosciences, London, United Kingdom

Amaia Mendiguren Arranz

Achucarro Basque Center for Neuroscience, Neurosciences, Leioa, Spain; IKERBASQUE Basque Foundation for Science, Neurosciences, Bilbao, Spain