Stroke Prevention Trials in Sickle Cell Anemia

Abstract

As part of an International Pediatric Stroke Study launched in 2002, the Stroke Prevention Trial in Sickle Cell Anemia (STOP) reports a reduction in the number of overt clinical strokes in children with critically high transcranial Doppler velocities (>200 cm/sec) who were regularly transfused.

Keywords

• stroke prevention trial in sickle cell anemia
• doppler screening
• hyperventilation