218 Prospective spatial immune cell profiling identifies features of the tumor-immune microenvironment associated with genomic alterations and patient survival in a 2,023 patient pan-cancer cohort

• Sara M Tolaney,
• James Lindsay,
• Michael Manos,
• Biagio Ricciuti,
• Anita Giobbie-Hurder,
• Scott J Rodig,
• Joao V Alessi,
• Mark M Awad,
• Sandro Santagata,
• Bruce E Johnson,
• Glenn J Hanna,
• Elio Adib,
• Jason Weirather,
• Xinan Wang,
• Bijaya Sharma,
• Kathleen Pfaff,
• Kristen D Felt,
• William Lotter,
• Panagiotis Konstantinopoulos,
• Madison Turner,
• Federica Pecci,
• Emma L Welsh,
• Stephanie M Jones,
• Jennifer O Altreuter,
• Ian D Dryg,
• Alessandro Di Federico,
• Malini M Gandhi,
• Sabrina J Chan,
• Marta Holovatska,
• Melissa E Hughes,
• O’Meara Tess A,
• Neal I Lindeman,
• Jennifer Curtis,
• Peter K Sorger,
• Ethan Cerami,
• Lynette M Sholl,
• Jonathan A Novak

Affiliations

Sara M Tolaney

1Dana-Farber Cancer Institute, Boston, MA, USA

James Lindsay

1Dana-Farber Cancer Institute, Boston, MA, USA

Michael Manos

1Dana-Farber Cancer Institute, Boston, MA, USA

Biagio Ricciuti

1Dana-Farber Cancer Institute, Boston, MA, USA

Anita Giobbie-Hurder

1Dana-Farber Cancer Institute, Boston, MA, USA

Scott J Rodig

2Brigham and Women’s Hospital, Boston, MA, USA

Joao V Alessi

1Dana-Farber Cancer Institute, Boston, MA, USA

Mark M Awad

1Dana-Farber Cancer Institute, Boston, MA, USA

Sandro Santagata

4Harvard Medical School, Boston, MA, USA

Bruce E Johnson

1Dana-Farber Cancer Institute, Boston, MA, USA

Glenn J Hanna

1Dana-Farber Cancer Institute, Boston, MA, USA

Elio Adib

1Dana-Farber Cancer Institute, Boston, MA, USA

Jason Weirather

1Dana-Farber Cancer Institute, Boston, MA, USA

Xinan Wang

3Harvard T.H. Chan School of Public Health, Boston, MA, USA

Bijaya Sharma

1Dana-Farber Cancer Institute, Boston, MA, USA

Kathleen Pfaff

1Dana-Farber Cancer Institute, Boston, MA, USA

Kristen D Felt

1Dana-Farber Cancer Institute, Boston, MA, USA

William Lotter

1Dana-Farber Cancer Institute, Boston, MA, USA

Panagiotis Konstantinopoulos

1Dana-Farber Cancer Institute, Boston, MA, USA

Madison Turner

1Dana-Farber Cancer Institute, Boston, MA, USA

Federica Pecci

1Dana-Farber Cancer Institute, Boston, MA, USA

Emma L Welsh

1Dana-Farber Cancer Institute, Boston, MA, USA

Stephanie M Jones

1Dana-Farber Cancer Institute, Boston, MA, USA

Jennifer O Altreuter

1Dana-Farber Cancer Institute, Boston, MA, USA

Ian D Dryg

1Dana-Farber Cancer Institute, Boston, MA, USA

Alessandro Di Federico

1Dana-Farber Cancer Institute, Boston, MA, USA

Malini M Gandhi

1Dana-Farber Cancer Institute, Boston, MA, USA

Sabrina J Chan

1Dana-Farber Cancer Institute, Boston, MA, USA

Marta Holovatska

1Dana-Farber Cancer Institute, Boston, MA, USA

Melissa E Hughes

1Dana-Farber Cancer Institute, Boston, MA, USA

O’Meara Tess A

1Dana-Farber Cancer Institute, Boston, MA, USA

Neal I Lindeman

2Brigham and Women’s Hospital, Boston, MA, USA

Jennifer Curtis

1Dana-Farber Cancer Institute, Boston, MA, USA

Peter K Sorger

4Harvard Medical School, Boston, MA, USA

Ethan Cerami

1Dana-Farber Cancer Institute, Boston, MA, USA

Lynette M Sholl

12Department of Pathology, Brigham and Women’s Hospital, Boston, MA, USA

Jonathan A Novak

2Brigham and Women’s Hospital, Boston, MA, USA