Frontiers in Endocrinology (Dec 2022)

To sleep or not to sleep: An Italian Control-IQ-uestion

  • Marta Bassi,
  • Marta Bassi,
  • Marina Francesca Strati,
  • Marina Francesca Strati,
  • Valentina Andreottola,
  • Valentina Andreottola,
  • Maria Grazia Calevo,
  • Giuseppe d’Annunzio,
  • Mohamad Maghnie,
  • Mohamad Maghnie,
  • Nicola Minuto

DOI
https://doi.org/10.3389/fendo.2022.996453
Journal volume & issue
Vol. 13

Abstract

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ObjectiveTandem Control-IQ is an advanced hybrid closed loop (AHCL) system with a Sleep Activity Mode to intensify glycemic control overnight. The aim of the study is to evaluate the effectiveness of using Sleep Mode or not among Tandem Control-IQ users.Research design and methodsWe performed a retrospective Tandem Control-IQ data download for patients followed at IRCCS G. Gaslini Pediatric Diabetes Centre. We divided the patients into group 1 (Sleep Mode users) and group 2 (non-users) and compared their overall glycemic data, particularly during nighttime.ResultsGroup 1 (n = 49) does not show better nocturnal glycemic control as expected when compared with group 2 (n = 34). Group 2 shows a nighttime TIR% of 69.50 versus 66.25 (p = 0.20). Only the patients who do not use Sleep Mode and with sensor and automatic mode use ≥90% reached TIR >70% during nighttime, as well as lower nocturnal TAR% (18.80 versus 21.78, p = 0.05).ConclusionsThis is the first study that evaluates the real-life effectiveness of the use of Sleep Mode in young patients with T1D. Control-IQ Sleep Activity Mode may not be as effective in Italian patients as in American patients due to the different habits.

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