Mechanistic insight for improving butenyl-spinosyn production through combined ARTP/UV mutagenesis and ribosome engineering in Saccharopolyspora pogona

• Xueli Zhao,
• Muhammad Hammad Hussain,
• Ali Mohsin,
• Zebo Liu,
• Zhixian Xu,
• Zhanxia Li,
• Weiqun Guo,
• Meijin Guo

Affiliations

Xueli Zhao

State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China

Muhammad Hammad Hussain

State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China

Ali Mohsin

State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China

Zebo Liu

State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China

Zhixian Xu

State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China

Zhanxia Li

Department of Respiratory Medicine, Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China

Weiqun Guo

Academy of National Food and Strategic Reserves Administration, Beijing, China

Meijin Guo

State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China