Nature Communications (Feb 2016)

Development of novel FP-based probes for live-cell imaging of nitric oxide dynamics

  • Emrah Eroglu,
  • Benjamin Gottschalk,
  • Suphachai Charoensin,
  • Sandra Blass,
  • Helmut Bischof,
  • Rene Rost,
  • Corina T. Madreiter-Sokolowski,
  • Brigitte Pelzmann,
  • Eva Bernhart,
  • Wolfgang Sattler,
  • Seth Hallström,
  • Tadeusz Malinski,
  • Markus Waldeck-Weiermair,
  • Wolfgang F. Graier,
  • Roland Malli

DOI
https://doi.org/10.1038/ncomms10623
Journal volume & issue
Vol. 7, no. 1
pp. 1 – 11

Abstract

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Nitric oxide is a volatile free radical second messenger with a large number of biological effects. Here Eroglu et al. develop genetically encoded fluorescent biosensors for nitric oxide and use them to visualise subcellular nitric oxide dynamics in single cells.