Clinical and anatomical portrait of patients with severe COVID-19
A. L. Kebina,
A. S. Sycheva,
A. L. Vertkin,
O. V. Zairatyants,
A. V. Pogonin,
M. V. Kuandykova,
O. I. Astakhova,
T. V. Astakhova,
M. A. Vasil’eva,
D. M. Zaichenko,
Yu. A. Kadushkina,
V. M. Kvashnina,
Yu. N. Kirichenko,
A. A. Masharova,
Yu. I. Ramazanova,
D. V. Rasko,
E. O. Skryabina,
M. K. Tamkaeva
Affiliations
A. L. Kebina
Federal State Budgetary Educational Institution of Higher Education, A. I. Evdokimov Moscow State Medical-Dental University; City Clinical Hospital named after S. I. Spasokukotsky Department of Health of Moscow
A. S. Sycheva
Federal State Budgetary Educational Institution of Higher Education, A. I. Evdokimov Moscow State Medical-Dental University; City Clinical Hospital named after S. I. Spasokukotsky Department of Health of Moscow
A. L. Vertkin
Federal State Budgetary Educational Institution of Higher Education, A. I. Evdokimov Moscow State Medical-Dental University; City Clinical Hospital named after S. I. Spasokukotsky Department of Health of Moscow
O. V. Zairatyants
Federal State Budgetary Educational Institution of Higher Education, A. I. Evdokimov Moscow State Medical-Dental University
A. V. Pogonin
City Clinical Hospital named after S. I. Spasokukotsky Department of Health of Moscow
M. V. Kuandykova
City Clinical Hospital named after S. I. Spasokukotsky Department of Health of Moscow
O. I. Astakhova
City Clinical Hospital named after S. I. Spasokukotsky Department of Health of Moscow
T. V. Astakhova
City Clinical Hospital named after S. I. Spasokukotsky Department of Health of Moscow
M. A. Vasil’eva
City Clinical Hospital named after S. I. Spasokukotsky Department of Health of Moscow
D. M. Zaichenko
City Clinical Hospital named after S. I. Spasokukotsky Department of Health of Moscow
Yu. A. Kadushkina
Federal State Budgetary Educational Institution of Higher Education, A. I. Evdokimov Moscow State Medical-Dental University; City Clinical Hospital named after S. I. Spasokukotsky Department of Health of Moscow
V. M. Kvashnina
City Clinical Hospital named after S. I. Spasokukotsky Department of Health of Moscow
Yu. N. Kirichenko
City Clinical Hospital named after S. I. Spasokukotsky Department of Health of Moscow
A. A. Masharova
City Clinical Hospital named after S. I. Spasokukotsky Department of Health of Moscow
Yu. I. Ramazanova
City Clinical Hospital named after S. I. Spasokukotsky Department of Health of Moscow
D. V. Rasko
Federal State Budgetary Educational Institution of Higher Education, A. I. Evdokimov Moscow State Medical-Dental University; City Clinical Hospital named after S. I. Spasokukotsky Department of Health of Moscow
E. O. Skryabina
City Clinical Hospital named after S. I. Spasokukotsky Department of Health of Moscow
M. K. Tamkaeva
City Clinical Hospital named after S. I. Spasokukotsky Department of Health of Moscow
The prevalence of somatic diseases in patients with pneumonia caused by SARS-CoV-2 viruses was assessed, the most common somatic diseases in patients, depending on gender and age groups were identified. 110 patients with viral pneumonia caused by SARSCoV-2 were included in the study. The presence of risk factors for the severe course of the disease, somatic pathology, epidemiological history, changes according to computed tomography and scores on the Charlson comorbidity scale were evaluated. The average age of patients with coronavirus infection caused by COVID-19 with an unfavorable outcome was 75 ± 1,3 years. The most common comorbid combined pathology in this group of patients is postinfarction cardiosclerosis, ischemic cardiomyopathy, and chronic cerebral ischemia. Of the risk factors for severe coronavirus infection, essential arterial hypertension is most common 93.6% (103 patients), age over 65 years old 81.8% (90 patients), diabetes mellitus 66.3% of cases (73 patients) and chronic heart failure 46.3% of cases (51 patients). In this group of patients, the average comorbidity index was 8.9 ± 0.3. Severe lethal disease is most often recorded in people of an older age group with diseases of the cardiovascular system, cerebrovascular pathology and malignant neoplasms. Even patients of young and older age groups had risk factors for poor prognosis. According to the study, the most unfavorable symptoms (fever above 38 оС, shortness of breath and weakness) occur first, 6 days before hospitalization, while the rest appear more often 3-5 days before hospitalization. Patients who have such risk factors as age over 65 years, arterial hypertension and heart failure in combination with symptoms such as fever above 38 оС, shortness of breath and weakness require immediate hospitalization, regardless of the level of hypoxemia and changes according to computer tomography, for further observation and treatment due to the high probability of death.
