Development of blood hemoglobin level early detection device based on a noninvasive optical platform
Irzaman,
Yaya Suryana,
Sabar Pambudi,
Tika Widayanti,
Renan Prasta Jenie,
Bayu Prastowo,
Nazopatul Patonah Har,
Vania Rahmawaty,
Muhammad Dahrul,
Aminullah,
Ade Kurniawan,
Ridwan Siskandar,
Ichsan Hardyanto,
Johan Iskandar,
Naufal Muharram Nurdin,
Arga Ardidarma,
Sri Kristiana Rahayu,
Husin Alatas
Affiliations
Irzaman
Department of Physics, Faculty of Mathematics and Natural Sciences, IPB University, Bogor, Indonesia
Yaya Suryana
National Research and Innovation Agency (BRIN), Serpong, Indonesia
Sabar Pambudi
National Research and Innovation Agency (BRIN), Serpong, Indonesia
Tika Widayanti
National Research and Innovation Agency (BRIN), Serpong, Indonesia
Renan Prasta Jenie
Department of Nutrition, Faculty of Health Science and Technology, Binawan University, Jakarta, Indonesia
Bayu Prastowo
Department of Physiotherapy, Faculty of Health Sciences, University of Muhammadiyah Malang, Malang, Indonesia
Nazopatul Patonah Har
Department of Physics, Faculty of Mathematics and Natural Sciences, IPB University, Bogor, Indonesia
Vania Rahmawaty
Department of Physics, Faculty of Mathematics and Natural Sciences, IPB University, Bogor, Indonesia
Muhammad Dahrul
Department of Physics, Faculty of Mathematics and Natural Sciences, IPB University, Bogor, Indonesia
Aminullah
Department of Food Technology and Nutrition, Faculty of Halal Food Sciences, Djuanda University, Bogor, Indonesia
Ade Kurniawan
Department of Physics, Faculty of Science and Technology, Islamic State University of Sunan Kalijaga, Yogyakarta, Indonesia
Ridwan Siskandar
Vocational School, IPB University, Bogor, Indonesia
Ichsan Hardyanto
Department of Physics, Faculty of Mathematics and Natural Sciences, IPB University, Bogor, Indonesia
Johan Iskandar
Vocational School of Computer Engineering, Pakuan University, Bogor, Indonesia
Naufal Muharram Nurdin
Department of Public Nutrition, Faculty of Human Ecology, IPB University, Bogor, Indonesia
Arga Ardidarma
PT Tesena Inovindo, Jakarta, Indonesia
Sri Kristiana Rahayu
PT Tesena Inovindo, Jakarta, Indonesia
Husin Alatas
Department of Physics, Faculty of Mathematics and Natural Sciences, IPB University, Bogor, Indonesia; Center for Transdisciplinary and Sustainability Sciences (CTSS), IPB University, Bogor, Indonesia; Corresponding author.
Blood hemoglobin levels are a reliable indicator for anemia screening, which generally uses an invasive system or takes blood using a syringe. Spectrophotometry can work by “substituting” the use of a phlebotomy tube needle with electromagnetic wave radiation or light. This study aims to develop and carry out a noninvasive diagnostic test for measuring hemoglobin levels. There are three main stages in this research: (i) measuring hemoglobin concentration and scanning an incident wavelength on standard hemoglobin solutions and blood controls, (ii) making a prototype variant of a noninvasive blood hemoglobin level measurement device, and (iii) testing the technology unit on the developed prototype. The measured hemoglobin value by the Trax Control Meter for low, middle, and high levels is almost the same as the expected range values, namely, 13.09, 16.8, and 17.81 g/dL, respectively. Three sets of device prototype variants were successfully developed: (i) the noninvasive blood hemoglobin level measuring device based on Raspberry Pi Prototype on Infant Finger and Thigh Probes, (ii) the level measuring prototype noninvasive hemoglobin in blood based on Internet of Things and WebServer, and (iii) the prototype of noninvasive blood hemoglobin level measuring device on in vitro probe with reflectance method. Testing the accuracy of the Biorad MeterTrax Trilevel using a multiformula regression calculation using the ZunZun server shows that the tool has an accuracy ranging from 0.12 to 0.30 g/dL.
