Respiratory Research (Oct 2020)

Are there pulmonary sequelae in patients recovering from COVID-19?

  • Paola Rogliani,
  • Luigino Calzetta,
  • Angelo Coppola,
  • Ermanno Puxeddu,
  • Gianluigi Sergiacomi,
  • Dejanira D’Amato,
  • Antonio Orlacchio

DOI
https://doi.org/10.1186/s12931-020-01550-6
Journal volume & issue
Vol. 21, no. 1
pp. 1 – 4

Abstract

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Abstract It has been recently hypothesized that infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may lead to fibrotic sequelae in patients recovering from coronavirus disease 2019 (COVID-19). In this observational study, hospitalized patients with COVID-19 had a HRCT of the chest performed to detect the extension of fibrotic abnormalities via Hounsfield Units (HU). At follow-up, the lung density significantly improved in both lungs and in each lobe of all patients, being in the normal range (− 950 to − 700 HU). This study provides preliminary evidence that hospitalized patients with mild-to-moderate forms of COVID-19 are not at risk of developing pulmonary fibrosis.

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