LOW DOSAGE ACETYLSALICYLIC ACID: A VARIETY OF FORMULATIONS

Abstract

The most prevalent formulation of the low-dosage (ld) acetylsalicylic acid (ASA) for prevention purposes is the gut soluble pill — 80,6% of the ldASA registered in pharmacy market. Formulations of ldASA mostly presented as ASA monodrugs (84,4%), containing only ASA as active substance, predominantly as 100 mg dosage. Amount of ASA of 81 mg has become widespread only in North America, that is related to nonmetric measurement system. Combinational ldASA with non-soluble antacide (magnesium hydroxide) are not broadly used throughout the world — 1,6% of all pharmacy market registered labels, and mostly in use in the regions of former USSR.

Keywords

• acetylsalicylic acid
• prevention
• cardiovascular diseases
• drug formulations
• marketing analysis