Hyperspectral in vivo analysis of normal skin chromophores and visualization of oncological pathologies

Abstract

In the paper, we present test results of methods for the noninvasive diagnosis of skin neoplasms, based on the hyperspectral registration of images by using a camera with an acousto-optic tunable filter. For the identification of oncological pathologies, an integral spectral index has been proposed for a set of concentric regions around the source of neoplasm growth for the tissue sample under study. As well as taking account of changes in the spectral properties of the tissue, the introduced index indirectly takes into account classical ABCD dermatoscopic features: asymmetry, border irregularity, color diversity, and the tumor diameter. Results of training set separating are presented and the applicability of the proposed approaches to the clinical practice is shown.

Keywords

• hyperspectral imaging
• chromophores
• melanin
• hemoglobin
• oncopathology
• malignant melanoma
• basal cell carcinoma
• acousto-optical video spectrometer
• optical density
• chromophore index
• classification