FUNCTIONAL AND DIFFUSION-TENSOR MAGNETIC RESONANCE IMAGING IN DETECTION OF ALZHEIMER’S DISEASE ON EARLY STAGES

Abstract

Alzheimer's disease (AD) is the most common form of dementia among neurodegenerative diseases. New advanced methods of magnetic resonance imaging, such as functional (fMRI) and diffusiontensor imaging (DT-MRI), can evaluate changes in brain matter of AD at the microstructural and functional levels and can be used in the diagnostics of this pathological process on early stages of cognitive impairment. In this review, a literature search was made in electronic databases and scientific libraries of PubMed, Medscape, Elsiever, Cyberleninka. The review highlighted the merits and demerits of fMRI and DT-MRI, the clinical application of this methods in diagnosis of AD on early stage were also assessed.

Keywords

• literary review
• dementia
• alzheimer's disease
• magnetic resonance imaging
• functional magnetic resonance imaging
• diffusion tensor imaging