Xin yixue (Nov 2024)

Research progress on acupuncture regulation of asthma related group 2 innate lymphoid cell function

  • DONG Min, LI Hao, PAN Jiaxin, ZHANG Kun, GUO Bin

DOI
https://doi.org/10.3969/j.issn.0253-9802.2024.11.013
Journal volume & issue
Vol. 55, no. 11
pp. 950 – 956

Abstract

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This paper reviews the role of innate lymphoid cells (ILC2s) in the pathogenesis of bronchial asthma and explores the evidence for acupuncture’s regulatory effects on ILC2s in asthma treatment. Preliminary findings suggest that acupuncture may mitigate airway inflammation, curb airway hyperresponsiveness, and enhance airway remodeling in asthma patients by modulating ILC2 secretion and migration. Despite these insights, several challenges remain, including the unclear pathways through which ILC2s are regulated by acupuncture in asthma, a scarcity of animal experiments and clinical studies, and a lack of understanding regarding how acupuncture might improve the mechanisms underlying hormone-resistant asthma via the ILC2 pathway.

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