How could hypoglycemia-inducing glycogen storage disease lead to hyperglycemia-induced mucormycosis?

Abstract

Mucormycosis is an increasingly frequent, difficult to diagnose, difficult to treat, often fatal infection, especially in patients with hyperglycemia from uncontrolled diabetes. Type I (von Gierke) glycogen storage disease is due to inherited deficiency of enzymes in glycogen metabolism, which causes hypoglycemia. This report is the case of a patient with von Gierke disease and a missed diagnosis of pulmonary mucormycosis. This report illustrates the importance of having a high index of suspicion for mucormycosis in the appropriate clinical context.

Keywords

• Mucor
• Lung Diseases
• Fungal
• Glycogen Storage Disease Type I
• Autopsy