Modeling lung perfusion abnormalities to explain early COVID-19 hypoxemia

Jacob Herrmann; Vitor Mori; Jason H. T. Bates; Béla Suki

doi:10.1038/s41467-020-18672-6

Nature Communications (Sep 2020)

Modeling lung perfusion abnormalities to explain early COVID-19 hypoxemia

Jacob Herrmann,
Vitor Mori,
Jason H. T. Bates,
Béla Suki

Affiliations

Jacob Herrmann: Department of Biomedical Engineering, Boston University
Vitor Mori: Department of Medicine, University of Vermont
Jason H. T. Bates: Department of Medicine, University of Vermont
Béla Suki: Department of Biomedical Engineering, Boston University

DOI: https://doi.org/10.1038/s41467-020-18672-6
Journal volume & issue: Vol. 11, no. 1
pp. 1 – 9

Abstract

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Early stages of the novel coronavirus disease (COVID-19) have been associated with silent hypoxia and poor oxygenation despite relatively small fractions of afflicted lung. Here, the authors present a mathematical model which reproduces the vascular pulmonary mechanisms observed in patients with early COVID-19.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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