Nature Communications (Jul 2022)
Mutations in DNA polymerase δ subunit 1 co-segregate with CMD2-type resistance to Cassava Mosaic Geminiviruses
- Yi-Wen Lim,
- Ben N. Mansfeld,
- Pascal Schläpfer,
- Kerrigan B. Gilbert,
- Narayanan N. Narayanan,
- Weihong Qi,
- Qi Wang,
- Zhenhui Zhong,
- Adam Boyher,
- Jackson Gehan,
- Getu Beyene,
- Zuh-Jyh Daniel Lin,
- Williams Esuma,
- Suhua Feng,
- Christelle Chanez,
- Nadine Eggenberger,
- Gerald Adiga,
- Titus Alicai,
- Steven E. Jacobsen,
- Nigel J. Taylor,
- Wilhelm Gruissem,
- Rebecca S. Bart
Affiliations
- Yi-Wen Lim
- Institute of Molecular Plant Biology, Department of Biology, ETH Zürich
- Ben N. Mansfeld
- Donald Danforth Plant Science Center
- Pascal Schläpfer
- Institute of Molecular Plant Biology, Department of Biology, ETH Zürich
- Kerrigan B. Gilbert
- Donald Danforth Plant Science Center
- Narayanan N. Narayanan
- Donald Danforth Plant Science Center
- Weihong Qi
- Functional Genomics Center Zurich, ETH Zurich and University of Zurich
- Qi Wang
- Donald Danforth Plant Science Center
- Zhenhui Zhong
- Department of Molecular, Cell and Developmental Biology, University of California Los Angeles
- Adam Boyher
- Donald Danforth Plant Science Center
- Jackson Gehan
- Donald Danforth Plant Science Center
- Getu Beyene
- Donald Danforth Plant Science Center
- Zuh-Jyh Daniel Lin
- Donald Danforth Plant Science Center
- Williams Esuma
- Root Crops Program, National Crops Resources Research Institute
- Suhua Feng
- Department of Molecular, Cell and Developmental Biology, University of California Los Angeles
- Christelle Chanez
- Institute of Molecular Plant Biology, Department of Biology, ETH Zürich
- Nadine Eggenberger
- Institute of Molecular Plant Biology, Department of Biology, ETH Zürich
- Gerald Adiga
- Root Crops Program, National Crops Resources Research Institute
- Titus Alicai
- Root Crops Program, National Crops Resources Research Institute
- Steven E. Jacobsen
- Department of Molecular, Cell and Developmental Biology, University of California Los Angeles
- Nigel J. Taylor
- Donald Danforth Plant Science Center
- Wilhelm Gruissem
- Institute of Molecular Plant Biology, Department of Biology, ETH Zürich
- Rebecca S. Bart
- Donald Danforth Plant Science Center
- DOI
- https://doi.org/10.1038/s41467-022-31414-0
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 11
Abstract
Cassava mosaic disease is caused by geminiviruses and suppresses cassava yields throughout the tropics. Here, the authors show that mutations in MePOLD1, encoding DNA polymerase δ subunit 1, co-segregate with CMD2, the major source of genetic resistance for this disease.
