POLYMORPHISM OF CANDIDATE GENES OF HEMOSTASIS DISORDERS IN PREGNANT WOMEN AFTER HAVING А(H1N1)PDM2009 INFLUENZA

D. A. Tarbaeva; T. E. Belokrinitskaya; N. N. Strambovskaya; L. I. Anokhova

Acta Biomedica Scientifica (Jul 2014)

POLYMORPHISM OF CANDIDATE GENES OF HEMOSTASIS DISORDERS IN PREGNANT WOMEN AFTER HAVING А(H1N1)PDM2009 INFLUENZA

D. A. Tarbaeva,
T. E. Belokrinitskaya,
N. N. Strambovskaya,
L. I. Anokhova

Affiliations

D. A. Tarbaeva: Chita State Medical Academy
T. E. Belokrinitskaya: Chita State Medical Academy
N. N. Strambovskaya: Chita State Medical Academy
L. I. Anokhova: Chita State Medical Academy

Journal volume & issue: Vol. 0, no. 4
pp. 46 – 50

Abstract

Read online

We studied polymorphisms of candidate genes of hemostasis disorders in 205 pregnant women after having A(H1N1) pdm2009 influenza during pregnancy and in 75 pregnant women who didn't have acute respiratory viral infections during pregnancy. Pregnant women with influenza were more often carriers of mutant alleles F2, genotypes F7:0976GA and F13:W3G> . Severe course of influenza is associated with genotypes F7:0976GA and PAI-1:4G4G. It was revealed that polymorphisms of genes F7:0976G>A, F13:103G>T and PAI-1:6755G>4G can be molecular predictors of complicated course of A(HlNl)pdm09 influenza in pregnant women.

Published in Acta Biomedica Scientifica

ISSN: 2541-9420 (Print); 2587-9596 (Online)
Publisher: Scientific Сentre for Family Health and Human Reproduction Problems
Country of publisher: Russian Federation
LCC subjects: Science
Website: http://actabiomedica.ru/en/

About the journal

Abstract

Keywords