Química Nova (Jan 2011)

Preparação de copolímeros à base de 2-vinilpiridina com propriedades bactericidas

  • Aline S. S. Valle,
  • Luciana C. Costa,
  • Mônica R. C. Marques,
  • Camila L. P. Silva,
  • Luiz Cláudio de Santa Maria,
  • Fábio Merçon,
  • Alcino Palermo de Aguiar

DOI
https://doi.org/10.1590/S0100-40422011000400005
Journal volume & issue
Vol. 34, no. 4
pp. 577 – 583

Abstract

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We report the development of two copolymers based on 2-vinylpyridine, styrene and divinylbenzene (2Vpy-Sty-DVB) with different porosity degrees. The copolymers were subsequently quaternized with methyl iodide. To prepare charge transfer complexes, the unmodified copolymers and their derivatives quaternized with methyl iodine were impregnated with iodine. The antibacterial properties of the polymers were evaluated in dilutions ranging from 10² to 10(7) cells/mL of the auxotrophic OHd5-K12 Escherichia coli strain. It was possible to obtain materials with complete antibacterial activity even in the highest cell concentrations tested.

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