Future Science OA (Jun 2020)

Surgery versus stereotactic radiotherapy for treatment of pulmonary metastases. A systematic review of literature

  • Francesco Londero,
  • William Grossi,
  • Angelo Morelli,
  • Orlando Parise,
  • Gianluca Masullo,
  • Cecilia Tetta,
  • Ugolino Livi,
  • Jos G Maessen,
  • Sandro Gelsomino

DOI
https://doi.org/10.2144/fsoa-2019-0120
Journal volume & issue
Vol. 6, no. 5

Abstract

Read online

It is not clear as to which is the best treatment among surgery and stereotactic radiotherapy (SBRT) for lung oligometastases. A systematic review of literature with a priori selection criteria was conducted on articles on the treatment of pulmonary metastases with surgery or SBRT. Only original articles with a population of patients of more than 50 were selected. After final selection, 61 articles on surgical treatment and 18 on SBRT were included. No difference was encountered in short-term survival between pulmonary metastasectomy and SBRT. In the long-term surgery seems to guarantee better survival rates. Mortality and morbidity after treatment are 0–4.7% and 0–23% for surgery, and 0–2% and 4–31% for SBRT. Surgical metastasectomy remains the treatment of choice for pulmonary oligometastases.

Keywords