Nature Communications (Aug 2021)
Impact of aging and exercise on skeletal muscle mitochondrial capacity, energy metabolism, and physical function
- L. Grevendonk,
- N. J. Connell,
- C. McCrum,
- C. E. Fealy,
- L. Bilet,
- Y. M. H. Bruls,
- J. Mevenkamp,
- V. B. Schrauwen-Hinderling,
- J. A. Jörgensen,
- E. Moonen-Kornips,
- G. Schaart,
- B. Havekes,
- J. de Vogel-van den Bosch,
- M. C. E. Bragt,
- K. Meijer,
- P. Schrauwen,
- J. Hoeks
Affiliations
- L. Grevendonk
- Department of Nutrition and Movement Sciences, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University
- N. J. Connell
- Department of Nutrition and Movement Sciences, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University
- C. McCrum
- Department of Nutrition and Movement Sciences, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University
- C. E. Fealy
- Department of Nutrition and Movement Sciences, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University
- L. Bilet
- Department of Nutrition and Movement Sciences, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University
- Y. M. H. Bruls
- Department of Radiology and Nuclear Medicine, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Center+
- J. Mevenkamp
- Department of Radiology and Nuclear Medicine, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Center+
- V. B. Schrauwen-Hinderling
- Department of Nutrition and Movement Sciences, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University
- J. A. Jörgensen
- Department of Nutrition and Movement Sciences, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University
- E. Moonen-Kornips
- Department of Nutrition and Movement Sciences, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University
- G. Schaart
- Department of Nutrition and Movement Sciences, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University
- B. Havekes
- Department of Nutrition and Movement Sciences, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University
- J. de Vogel-van den Bosch
- Danone Nutricia Research
- M. C. E. Bragt
- Friesland-Campina
- K. Meijer
- Department of Nutrition and Movement Sciences, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University
- P. Schrauwen
- Department of Nutrition and Movement Sciences, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University
- J. Hoeks
- Department of Nutrition and Movement Sciences, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University
- DOI
- https://doi.org/10.1038/s41467-021-24956-2
- Journal volume & issue
-
Vol. 12,
no. 1
pp. 1 – 17
Abstract
Aging is associated with a progressive loss of muscle function. Here the authors characterize mitochondrial capacity and muscle function in young and older adults with similar habitual physical activity and also compared to older adults with exercise training or with physical impairment.
