The Additional Value of <sup>18</sup>F-FDG PET and MRI in Patients with Glioma: A Review of the Literature from 2015 to 2020

Natale Quartuccio; Riccardo Laudicella; Antonio Vento; Salvatore Pignata; Maria Vittoria Mattoli; Rossella Filice; Alessio Danilo Comis; Annachiara Arnone; Sergio Baldari; Manlio Cabria; Angelina Cistaro

doi:10.3390/diagnostics10060357

Diagnostics (May 2020)

The Additional Value of <sup>18</sup>F-FDG PET and MRI in Patients with Glioma: A Review of the Literature from 2015 to 2020

Natale Quartuccio,
Riccardo Laudicella,
Antonio Vento,
Salvatore Pignata,
Maria Vittoria Mattoli,
Rossella Filice,
Alessio Danilo Comis,
Annachiara Arnone,
Sergio Baldari,
Manlio Cabria,
Angelina Cistaro

Affiliations

Natale Quartuccio: Nuclear Medicine Unit, A.R.N.A.S. Ospedali Civico, Di Cristina e Benfratelli, 90127 Palermo, Italy
Riccardo Laudicella: Nuclear Medicine Unit, Department of Biomedical and Dental Sciences and Morpho-Functional Imaging, University of Messina, 98125 Messina, Italy
Antonio Vento: Nuclear Medicine Unit, Department of Biomedical and Dental Sciences and Morpho-Functional Imaging, University of Messina, 98125 Messina, Italy
Salvatore Pignata: Nuclear Medicine Unit, Department of Biomedical and Dental Sciences and Morpho-Functional Imaging, University of Messina, 98125 Messina, Italy
Maria Vittoria Mattoli: Department of Neurosciences, Imaging and Clinical Sciences, “G. d’Annunzio” University, 66100 Chieti, Italy
Rossella Filice: Nuclear Medicine Unit, Department of Biomedical and Dental Sciences and Morpho-Functional Imaging, University of Messina, 98125 Messina, Italy
Alessio Danilo Comis: Nuclear Medicine Unit, Department of Biomedical and Dental Sciences and Morpho-Functional Imaging, University of Messina, 98125 Messina, Italy
Annachiara Arnone: Nuclear Medicine Unit, A.R.N.A.S. Ospedali Civico, Di Cristina e Benfratelli, 90127 Palermo, Italy
Sergio Baldari: Nuclear Medicine Unit, Department of Biomedical and Dental Sciences and Morpho-Functional Imaging, University of Messina, 98125 Messina, Italy
Manlio Cabria: Nuclear Medicine Department, Ente Ospedaliero Ospedali Galliera, Italy, Mura delle Cappuccine, 14, 16128 Genova, Italy
Angelina Cistaro: Nuclear Medicine Department, Ente Ospedaliero Ospedali Galliera, Italy, Mura delle Cappuccine, 14, 16128 Genova, Italy

DOI: https://doi.org/10.3390/diagnostics10060357
Journal volume & issue: Vol. 10, no. 6
p. 357

Abstract

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Aim: Beyond brain computed tomography (CT) scan, Magnetic Resonance Imaging (MRI) and Positron Emission Tomography (PET) hold paramount importance in neuro-oncology. The aim of this narrative review is to discuss the literature from 2015 to 2020, showing advantages or complementary information of fluorine-18 fluorodeoxyglucose (18F-FDG) PET imaging to the anatomical and functional data offered by MRI in patients with glioma. Methods: A comprehensive Pubmed/MEDLINE literature search was performed to retrieve original studies, with a minimum of 10 glioma patients, published from 2015 until the end of April 2020, on the use of 18F-FDG PET in conjunction with MRI. Results: Twenty-two articles were selected. Combined use of the two modalities improves the accuracy in predicting prognosis, planning treatments, and evaluating recurrence. Conclusion: According to the recent literature, 18F-FDG PET provides different and complementary information to MRI and may enhance performance in the whole management of gliomas. Therefore, integrated PET/MRI may be particularly useful in gliomas, since it could provide accurate morphological and metabolic information in one-shoot examination and improve the diagnostic value compared to each of procedures.

Published in Diagnostics

ISSN: 2075-4418 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Medicine: Medicine (General)
Website: http://www.mdpi.com/journal/diagnostics

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