Репродуктивная эндокринология (Dec 2017)
Modern approaches to correction of vaginal microbiocenosis at the stage of preconceptional preparation
Abstract
Today in Ukraine and in the world there is a tendency to increase the age of both primiparous women and women, which delay the birth of the second child. This creates certain risks with regard to the increase in the population of women of reproductive age the frequency of extragenital pathology and diseases of the female genital area, in particular, infectious genesis. In this regard, correction of the vaginal microbiocenosis at the stage of pre-conceptual preparation acquires special significance. The aim of the study to evaluate the effectiveness of the drug Depantol for the treatment of nonspecific vulvovaginitis at the stage of pre-conceptual preparation. Under supervision there were 45 women aged 24–32 years. The diagnosis of non-specific vulvovaginitis verified according to the clinical and laboratory methods of the study. All patients was prescribed the drug Depantol by 1 suppository 2 times a day for 10 days. Treatment efficacy was evalued according to the clinical and microbiological examination before treatment, and at 1 and 3 months after treatment. As a result of the study, the clinical and laboratory efficacy of the proposed therapy was substantiated. The absence of subjective symptoms after treatment was ascertained, bacteriological study confirmed the effectiveness of therapy in 95.6% of cases. The author of the study notes that the drug Depantol is highly effective in relation to the main pathogens of non-specific vulvovaginitis, which makes it the drug of choice in preconception preparation. Depantol does not interfere with the functional activity of lactic acid bacteria, which contributes to the rapid restoration of the normal biotope of the vagina and creates favorable conditions for conception.
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