Communications Biology (Aug 2022)

A tissue-level phenome-wide network map of colocalized genes and phenotypes in the UK Biobank

  • Ghislain Rocheleau,
  • Iain S. Forrest,
  • Áine Duffy,
  • Shantanu Bafna,
  • Amanda Dobbyn,
  • Marie Verbanck,
  • Hong-Hee Won,
  • Daniel M. Jordan,
  • Ron Do

DOI
https://doi.org/10.1038/s42003-022-03820-z
Journal volume & issue
Vol. 5, no. 1
pp. 1 – 9

Abstract

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A phenome-wide genomic analysis on the UK Biobank cohort links >9,000 co-localized genes and >1,400 human phenotypes across a broad selection of human tissues, representing a useful resource for the investigation of relationships between gene expression, tissues, and human diseases.