Journal of Clinical Medicine (Oct 2023)
Recommendations for the Clinical Approach to Immune Thrombocytopenia: Spanish ITP Working Group (GEPTI)
- María Eva Mingot-Castellano,
- Mariana Canaro Hirnyk,
- Blanca Sánchez-González,
- María Teresa Álvarez-Román,
- Abelardo Bárez-García,
- Ángel Bernardo-Gutiérrez,
- Silvia Bernat-Pablo,
- Estefanía Bolaños-Calderón,
- Nora Butta-Coll,
- Gonzalo Caballero-Navarro,
- Isabel Socorro Caparrós-Miranda,
- Laura Entrena-Ureña,
- Luis Fernando Fernández-Fuertes,
- Luis Javier García-Frade,
- María del Carmen Gómez del Castillo,
- Tomás José González-López,
- Carlos Grande-García,
- José María Guinea de Castro,
- Isidro Jarque-Ramos,
- Reyes Jiménez-Bárcenas,
- Elsa López-Ansoar,
- Daniel Martínez-Carballeira,
- Violeta Martínez-Robles,
- Emilio Monteagudo-Montesinos,
- José Antonio Páramo-Fernández,
- María del Mar Perera-Álvarez,
- Inmaculada Soto-Ortega,
- David Valcárcel-Ferreiras,
- Cristina Pascual-Izquierdo
Affiliations
- María Eva Mingot-Castellano
- Hematology Department, Hospital Universitario Virgen del Rocío, Instituto de Biomedicina de Sevilla, 41013 Sevilla, Spain
- Mariana Canaro Hirnyk
- Hematology Department, Hospital Son Espases, Palma de Mallorca, 07210 Palma, Spain
- Blanca Sánchez-González
- Hematology Department, Hospital del Mar, 08003 Barcelona, Spain
- María Teresa Álvarez-Román
- Hematology Department, Hospital Universitario La Paz-IdiPAZ, Universidad Autónoma de Madrid, 28046 Madrid, Spain
- Abelardo Bárez-García
- Hematology Department, Hospital de Ávila, 05004 Ávila, Spain
- Ángel Bernardo-Gutiérrez
- Hematology Department, Hospital Central de Asturias, 33011 Oviedo, Spain
- Silvia Bernat-Pablo
- Hematology Department, Hospital Universitario de la Plana, 12540 Villarreal, Spain
- Estefanía Bolaños-Calderón
- Hematology Department, Hospital Clínico San Carlos, IML, IdISSC, 28040 Madrid, Spain
- Nora Butta-Coll
- Hematology Department, Instituto de Investigación Hospital Universitario La Paz (IdiPAZ), 28046 Madrid, Spain
- Gonzalo Caballero-Navarro
- Hematology Department, Hospital Universitario Miguel Servet, 50009 Zaragoza, Spain
- Isabel Socorro Caparrós-Miranda
- Hematology Department, Hospital Universitario Virgen de la Victoria, 29010 Málaga, Spain
- Laura Entrena-Ureña
- Hematology Department, Hospital Universitario Virgen de las Nieves, 18014 Granada, Spain
- Luis Fernando Fernández-Fuertes
- Hematology Department, Complejo Hospitalario Universitario Insular Materno-Infantil, 35016 Las Palmas de Gran Canaria, Spain
- Luis Javier García-Frade
- Hematology Department, Hospital Universitario Río Hortega, Gerencia Regional de Salud de Castilla y León, 47012 Valladolid, Spain
- María del Carmen Gómez del Castillo
- Hematology Department, Hospital General de la Coruña, 15006 A Coruña, Spain
- Tomás José González-López
- Hematology Department, Hospital Universitario de Burgos, 09006 Burgos, Spain
- Carlos Grande-García
- Hematology Department, Clínica Universidad de Navarra, 28022 Madrid, Spain
- José María Guinea de Castro
- Hematology Department, Hospital Universitario de Araba, 01009 Vitoria-Gasteiz, Spain
- Isidro Jarque-Ramos
- Hematology Department, Hospital Universitario y Politécnico La Fe, 46026 Valencia, Spain
- Reyes Jiménez-Bárcenas
- Hematology Department, Hospital Serranía de Ronda, 29400 Ronda, Spain
- Elsa López-Ansoar
- Hematology Department, Complejo Hospitalario Universitario de Vigo, 36312 Vigo, Spain
- Daniel Martínez-Carballeira
- Hematology Department, Hospital Central de Asturias, 33011 Oviedo, Spain
- Violeta Martínez-Robles
- Hematology Department, Complejo Asistencial Universitario de León, 24008 León, Spain
- Emilio Monteagudo-Montesinos
- Pediatric Department, Hospital Universitario y Politécnico La Fe, 46026 Valencia, Spain
- José Antonio Páramo-Fernández
- Hematology Department, Clínica Universidad de Navarra, 31008 Pamplona, Spain
- María del Mar Perera-Álvarez
- Hematology Department, Hospital Universitario de Gran Canaria Doctor Negrín, 35010 Las Palmas de Gran Canaria, Spain
- Inmaculada Soto-Ortega
- Hematology Department, Hospital Central de Asturias, 33011 Oviedo, Spain
- David Valcárcel-Ferreiras
- Hematology Department, Vall d’Hebron Instituto de Oncología (VHIO), Universitat Autònoma de Barcelona, 08035 Barcelona, Spain
- Cristina Pascual-Izquierdo
- Hematology Department, Hospital General Universitario Gregorio Marañón (HGUGM) Madrid, Instituto de Investigación Gregorio Marañón, 28007 Madrid, Spain
- DOI
- https://doi.org/10.3390/jcm12206422
- Journal volume & issue
-
Vol. 12,
no. 20
p. 6422
Abstract
Primary immune thrombocytopenia (ITP) is a complex autoimmune disease whose hallmark is a deregulation of cellular and humoral immunity leading to increased destruction and reduced production of platelets. The heterogeneity of presentation and clinical course hampers personalized approaches for diagnosis and management. In 2021, the Spanish ITP Group (GEPTI) of the Spanish Society of Hematology and Hemotherapy (SEHH) updated a consensus document that had been launched in 2011. The updated guidelines have been the reference for the diagnosis and management of primary ITP in Spain ever since. Nevertheless, the emergence of new tools and strategies makes it advisable to review them again. For this reason, we have updated the main recommendations appropriately. Our aim is to provide a practical tool to facilitate the integral management of all aspects of primary ITP management.
Keywords
- primary immune thrombocytopenia
- glucocorticoids
- intravenous immunoglobulins
- fostamatinib
- rituximab
- recommendations
