Structural Dynamics (Jul 2015)
Simple convergent-nozzle aerosol injector for single-particle diffractive imaging with X-ray free-electron lasers
- R. A. Kirian,
- S. Awel,
- N. Eckerskorn,
- H. Fleckenstein,
- M. Wiedorn,
- L. Adriano,
- S. Bajt,
- M. Barthelmess,
- R. Bean,
- K. R. Beyerlein,
- L. M. G. Chavas,
- M. Domaracky,
- M. Heymann,
- D. A. Horke,
- J. Knoska,
- M. Metz,
- A. Morgan,
- D. Oberthuer,
- N. Roth,
- T. Sato,
- P. L. Xavier,
- O. Yefanov,
- A. V. Rode,
- J. Küpper,
- H. N. Chapman
Affiliations
- R. A. Kirian
- Center for Free-Electron Laser Science, DESY, 22607 Hamburg, Germany
- S. Awel
- Center for Free-Electron Laser Science, DESY, 22607 Hamburg, Germany
- N. Eckerskorn
- Laser Physics Centre, Research School of Physics and Engineering, Australian National University, Canberra, Australia
- H. Fleckenstein
- Center for Free-Electron Laser Science, DESY, 22607 Hamburg, Germany
- M. Wiedorn
- Center for Free-Electron Laser Science, DESY, 22607 Hamburg, Germany
- L. Adriano
- Deutsches Elektronen-Synchrotron DESY, 22607 Hamburg, Germany
- S. Bajt
- Deutsches Elektronen-Synchrotron DESY, 22607 Hamburg, Germany
- M. Barthelmess
- Center for Free-Electron Laser Science, DESY, 22607 Hamburg, Germany
- R. Bean
- European XFEL GmbH, 22761 Hamburg, Germany
- K. R. Beyerlein
- Center for Free-Electron Laser Science, DESY, 22607 Hamburg, Germany
- L. M. G. Chavas
- Center for Free-Electron Laser Science, DESY, 22607 Hamburg, Germany
- M. Domaracky
- Center for Free-Electron Laser Science, DESY, 22607 Hamburg, Germany
- M. Heymann
- Center for Free-Electron Laser Science, DESY, 22607 Hamburg, Germany
- D. A. Horke
- Center for Free-Electron Laser Science, DESY, 22607 Hamburg, Germany
- J. Knoska
- Center for Free-Electron Laser Science, DESY, 22607 Hamburg, Germany
- M. Metz
- Center for Free-Electron Laser Science, DESY, 22607 Hamburg, Germany
- A. Morgan
- Center for Free-Electron Laser Science, DESY, 22607 Hamburg, Germany
- D. Oberthuer
- Center for Free-Electron Laser Science, DESY, 22607 Hamburg, Germany
- N. Roth
- Center for Free-Electron Laser Science, DESY, 22607 Hamburg, Germany
- T. Sato
- Center for Free-Electron Laser Science, DESY, 22607 Hamburg, Germany
- P. L. Xavier
- Center for Free-Electron Laser Science, DESY, 22607 Hamburg, Germany
- O. Yefanov
- Center for Free-Electron Laser Science, DESY, 22607 Hamburg, Germany
- A. V. Rode
- Laser Physics Centre, Research School of Physics and Engineering, Australian National University, Canberra, Australia
- J. Küpper
- Center for Free-Electron Laser Science, DESY, 22607 Hamburg, Germany
- H. N. Chapman
- Center for Free-Electron Laser Science, DESY, 22607 Hamburg, Germany
- DOI
- https://doi.org/10.1063/1.4922648
- Journal volume & issue
-
Vol. 2,
no. 4
pp. 041717 – 041717-12
Abstract
A major challenge in high-resolution x-ray free-electron laser-based coherent diffractive imaging is the development of aerosol injectors that can efficiently deliver particles to the peak intensity of the focused X-ray beam. Here, we consider the use of a simple convergent-orifice nozzle for producing tightly focused beams of particles. Through optical imaging we show that 0.5 μm particles can be focused to a full-width at half maximum diameter of 4.2 μm, and we demonstrate the use of such a nozzle for injecting viruses into a micro-focused soft-X-ray FEL beam.
