بیولوژی کاربردی (Sep 2022)
A comparative study of the effects of hydroalcoholic extracts of purslane (Portulaca oleracea L.) and henna leaves (Lawsonia inermis L.) on wound healing in male Wistar rats
Abstract
Objectives: One of the medicinal plants known in traditional medicine, henna with the scientific name Lawsonia inermis L. comes from the Lythraceae family and purslane with the scientific name Portulaca oleracea L. comes from the Portulacaceae family. According to the compounds present in these plants, many properties such as antimicrobial, anti-inflammatory, wound healing, trypsin inhibitory and antioxidant properties have been reported for them. Materials and Methods: This study was conducted on 24 male rats in the weight range of 200±20 grams, which were divided into 4 groups of six. Wounds 2 cm long were created on the back skin of mice: the first group was kept without treatment as a control, the second group was treated with Esrin (negative control) and the other two groups were treated with ointments made of henna and purslane with a concentration of 50% by weight. -Weight was used in the daily basis of Esrin. The area of the wound was measured daily from the second to the fourteenth day with Autocade software. The data were analyzed using SPSS software at a significance level of p<0.05. Findings: The decrease in wound area was significantly higher in all groups treated with purslane and henna. Purslane showed a better effect. Conclusion: Henna and purslane ointment can be used as effective substances in the treatment of skin wounds by significantly reducing the healing time and wound area.
