Emerging Infectious Diseases (May 2019)

Value of PCR, Serology, and Blood Smears for Human Granulocytic Anaplasmosis Diagnosis, France

  • Yves Hansmann,
  • Benoit Jaulhac,
  • Pierre Kieffer,
  • Martin Martinot,
  • Elisabeth Wurtz,
  • Régis Dukic,
  • Geneviève Boess,
  • André Michel,
  • Christophe Strady,
  • Jean François Sagez,
  • Nicolas Lefebvre,
  • Emilie Talagrand-Reboul,
  • Xavier Argemi,
  • Sylvie De Martino

DOI
https://doi.org/10.3201/eid2505.171751
Journal volume & issue
Vol. 25, no. 5
pp. 996 – 998

Abstract

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We prospectively examined the effectiveness of diagnostic tests for anaplasmosis using patients with suspected diagnoses in France. PCR (sensitivity 0.74, specificity 1) was the best-suited test. Serology had a lower specificity but higher sensitivity when testing acute and convalescent samples. PCR and serology should be used in combination for anaplasmosis diagnosis.

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