Clinical correlates of common corneal neovascular diseases:a literature review

Abstract

A large subset of corneal pathologies involves the formation of new blood and lymph vessels (neovascularization), leading to compromised visual acuity. This article aims to review the clinical causes and presentations of corneal neovascularization (CNV) by examining the mechanisms behind common CNV-related corneal pathologies, with a particular focus on herpes simplex stromal keratitis, contact lenses-induced keratitis and CNV secondary to keratoplasty. Moreover, we reviewed CNV in the context of different types of corneal transplantation and keratoprosthesis, and summarized the most relevant treatments available so far.

Keywords

• cornea
• neovascularization
• herpes simplex keratitis
• keratoplasty
• contact lens
• keratoprosthesis
• keratoprosthesis