Latest Research Development in Histone Acetylation in the Pathogenesis of Asthma

Abstract

Asthma is primarily marked by airway hyperresponsiveness, inflammation, and remodeling. Histone acetylation is one of the most common epigenetic modifications that regulates histone acetyltransferase and histone deacetylase, and imbalanced regulation may lead to pathological changes. We reviewed the advances in histone acetylation in the pathogenesis of asthma in recent five years, revealing the direction of systematic and in-depth research, in order to provide evidence for clinical treatment.

Keywords

• |asthma|histone acetylation|histone acetyltransferase|histone deacetylase|review