Klebsiella Pneumoniaeoxa-48 in a Urology Patient: Case Report

Abstract

We present an isolate of Klebsiella pneumoniaeOXA-48 isolated in a 68-year-old man who underwent radical prostatectomy due to prostate cancer. Th e antibiotic susceptibility testing to a wide range of antibiotics was performed by disk diffusion method and determination of minimal inhibitory concentrations. Th e isolate was classified as multidrug-resistant. It showed intermediate susceptibility to imipenem and meropenem, resistance to ertapenem, and sensitivity only to colistin, amikacin, and trimethoprim-sulfamethoxazole. Th e isolate was positive for ESBLs, negative for AmpC. Polymerase chain reaction and sequencing revealed blaOXA-48, blaCTX-M-15 and blaSHV-11. The plasmid encoding OXA-48 ß-lactamase did not belong to any known PCR-based replicon typing. According to genotyping, the isolate belonged to ST37.

Keywords

• Klebsiella pneumoniae – isolation and purification
• Klebsiella infections
• Prostatectomy – complications
• Case reports