Lipophilic Gold Grating for SERS Detection of Biological Objects

Abstract

We introduce label-free plasmon-active platform based on ordered gold gratings with the covalently modified surface for detection of lipophilic bioobjects. Alkylbenzene groups with different chain length (CH3-, C4H9-, C10H21- and C16H33) were grafted spontaneously and electrochemically for improvement of affinity with lipophilic compounds. Modified grating surfaces were characterized by XPS, CVA, wettability, AFM and Raman spectroscopy techniques.

Keywords

• SERS
• sensors
• diazonium salts
• surface modification
• cholesterol