Frontiers in Public Health (Feb 2023)

Association between urinary nickel with obesity status in adults: A cross-sectional study

  • Gao-Xiang Wang,
  • Gao-Xiang Wang,
  • Bao-Li Huang,
  • Jun-Tong Li,
  • Jun-Tong Li,
  • Ze-Bin Fang,
  • Le-Yi Feng,
  • Heng-Xia Zhao,
  • Shu-Fang Chu,
  • De-Liang Liu,
  • Hui-Lin Li

DOI
https://doi.org/10.3389/fpubh.2023.1094062
Journal volume & issue
Vol. 11

Abstract

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ObjectivesThe prevalence of obesity is on the rise and is connected to numerous factors. However, the relationship between obesity and nickel has never been investigated. Our study aimed to explore the association between urinary nickel and obesity Status in adults.MethodsFrom the 2017–2018 National Health and Nutrition Examination Surveys (NHANES), 1,705 participants ≥18 years of age were enrolled. To explore further the relationship among urinary nickel, body mass index (BMI), and waist circumference(WC), Weighted multivariate linear regression analyses and further subgroup analyzes were conducted.ResultsUrinary nickel does not correlate with BMI level but positively correlates with WC. In the subgroup analyzed according to sex, Urinary nickel has a positive correlation with BMI and WC in males but has a negative correlation in females. Secondary stratification analysis according to sex and race, Urinary nickel positively correlates with BMI in White males. It also positively correlates with WC in both White and Black males.ConclusionsA correlation was found between urinary nickel levels and BMI and WC in adult males. Adult men, especially those already obese, may need to reduce nickel exposure.

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