Potential adverse effects of long term use of Proton Pump Inhibitors

Abstract

Proton-Pump Inhibitors (PPIs) have changed the therapy of numerous upper gastrointestinal tract disorders; but their use is not without risk of adverse effects. Recent studies suggest more serious adverse events with chronic use of PPIs. Because of these risks, clinicians should reassess individual patient’s needs for chronic PPI therapy.

Keywords

• Proton Pump Inhibitors
• Side effects
• Osteoporosis
• Clostridium difficile
• Myocardia