Superficial intraventricular surface siderosis brain

Edlira Harizi, MD; Kledisa Shemsi, MD; Ilir Ahmetgjekaj, MD, PhD; Anusha Parisapogu, MBBS; Keti Mamillo, MD; Fjolla Hyseni, MD, PhDc; Simmy Lahori, MBBS; Kampa Prathima, MBBS; Chandalji Naik Banavath, MBBS; Zaina Syed, MD; Srikrishnan Pichuthirumalai, MBBS; Juna Musa, MD; Jasmine Saini, MD; Arieta Hasani Alidema, MD; Valon Vokshi, MD; Mohammad Abubaker Siddique, MBBS

Radiology Case Reports (Nov 2022)

Superficial intraventricular surface siderosis brain

Edlira Harizi, MD,
Kledisa Shemsi, MD,
Ilir Ahmetgjekaj, MD, PhD,
Anusha Parisapogu, MBBS,
Keti Mamillo, MD,
Fjolla Hyseni, MD, PhDc,
Simmy Lahori, MBBS,
Kampa Prathima, MBBS,
Chandalji Naik Banavath, MBBS,
Zaina Syed, MD,
Srikrishnan Pichuthirumalai, MBBS,
Juna Musa, MD,
Jasmine Saini, MD,
Arieta Hasani Alidema, MD,
Valon Vokshi, MD,
Mohammad Abubaker Siddique, MBBS

Affiliations

Edlira Harizi, MD: Department of Neurology, Regional Hospital Durres, Albania
Kledisa Shemsi, MD: Regional Hospital Durres, Tirana, Albania
Ilir Ahmetgjekaj, MD, PhD: University Clinical Center, Clinic of Radiology, Pristina, Kosovo
Anusha Parisapogu, MBBS: Department of Infectious Diseases, Mayo Clinic, Rochester, NY, USA
Keti Mamillo, MD: Department of Anesthesiology, University Medical Center of Tirana “Mother Teresa”, Tirana, Albania
Fjolla Hyseni, MD, PhDc: Department of Pediatrics, NYU Langone Health, New York, NY, USA; Corresponding author.
Simmy Lahori, MBBS: Department of Radiology, Mayo Clinic, Rochester, NY, USA
Kampa Prathima, MBBS: Lifetime Wellness Rx International Ltd, Bengaluru, India
Chandalji Naik Banavath, MBBS: Guntur Medical College, Andhra Pradesh, India
Zaina Syed, MD: Biochemistry, Hunter College CUNY, New York, NY, USA
Srikrishnan Pichuthirumalai, MBBS: Sakra World Hospital, Bengaluru, India
Juna Musa, MD: Department of Endocrinology, Diabetes and Nutrition, Mayo Clinic, Rochester, NY, USA
Jasmine Saini, MD: Department of Endocrinology, Mayo Clinic, Rochester, NY, USA
Arieta Hasani Alidema, MD: University for Business and Technology (UBT), Pristina, Kosovo
Valon Vokshi, MD: Department of Anesthesiology, University Clinical Center of Kosovo, Pristina, Kosovo
Mohammad Abubaker Siddique, MBBS: North East Medical College & Hospital, Sylhet, Bangladesh

Journal volume & issue: Vol. 17, no. 11
pp. 4152 – 4155

Abstract

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Superficial siderosis of the central nervous system is a chronic condition characterized by hemosiderin deposition in the brain and spinal cord. It's diagnosed by brain MRI. It can be caused by low-grade extravasation of blood into the subarachnoid space of the brain. There are 2 types of superficial siderosis cortical and infratentorial. Although asymptomatic in many cases; Cerebellar-predominant siderosis, a subtype of infratentorial, can affect hearing, gait, and even muscles. In this report, we present a case of a 51-year old female with complaints of hearing loss, unsteadiness in his lower limb, and spastic paresis. During MRI neuroimaging, we noticed findings of hypointensity areas within the brainstem and cerebellum, probably due to hemosiderin deposition. Based on the MRI findings, the patient was diagnosed with superficial siderosis. The patient was started on deferiprone and followed for the consecutive 18 months. Moderate improvement of the hearing loss and ataxia was noted while no change in muscle force. However, the repetitive MRI did not reveal any changes compared to the previous one.

Published in Radiology Case Reports

ISSN: 1930-0433 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Medicine (General): Medical physics. Medical radiology. Nuclear medicine
Website: https://www.sciencedirect.com/journal/radiology-case-reports

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