Nature Communications (Jul 2017)

Precise inhibitory microcircuit assembly of developmentally related neocortical interneurons in clusters

  • Xin-Jun Zhang,
  • Zhizhong Li,
  • Zhi Han,
  • Khadeejah T. Sultan,
  • Kun Huang,
  • Song-Hai Shi

DOI
https://doi.org/10.1038/ncomms16091
Journal volume & issue
Vol. 8, no. 1
pp. 1 – 16

Abstract

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Developmental neuroscientists have long asked if clonally-related neurons retain functional relationships after maturation. The authors show that sparsely labelled neocortical interneurons in clusters with high possibility of clonal relation preferentially form electrical, but not chemical, synapses.