Rare Tumors (Jul 2023)

Granular cell tumor of the lung and tracheobronchial tree: Two case-presentation with a review of the literature

  • Yoldez Houcine Assistant professor,
  • Mouna Mlika,
  • Chirine Moussa,
  • Houda Rouis,
  • Emna Brahem,
  • Olfa Ismail,
  • Sonia Maȃlej,
  • Faouzi El Mezni

DOI
https://doi.org/10.1177/20363613231187822
Journal volume & issue
Vol. 15

Abstract

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Pulmonary granular cells tumors (CGT) are rare tumors, that derive from Schwann cells. In the tracheobronchial and pulmonary tree, they remain a diagnostic challenge. There are no well-established criteria to differentiate between benign, atypical, and malignant GCT. Moreover, its real frequency in the respiratory tract is still unknown. Here, we represent 2 cases of bronchial and lung GCTs. We aim to highlight the frequency of all clinicopathological characteristics of this rare tumor in the tracheobronchial and pulmonary tree location based on our cases and the available literature in a large systematic review.