Life (Nov 2023)

Imaging of Strictures in Crohn’s Disease

  • Laura Maria Minordi,
  • Luigi Larosa,
  • Antonio Bevere,
  • Francesca Bice D’Angelo,
  • Antonio Pierro,
  • Savino Cilla,
  • Annemilia Del Ciello,
  • Franco Scaldaferri,
  • Brunella Barbaro

DOI
https://doi.org/10.3390/life13122283
Journal volume & issue
Vol. 13, no. 12
p. 2283

Abstract

Read online

Crohn’s disease (CD) is a chronic inflammation of the digestive tract, and it frequently affects young patients. It can involve any intestinal segment, even though it frequently affects the distal ileum. Up to 80% of patients with CD present with inflammatory behavior, and 5% to 28% develop stricturing disease. Based on the predominant mechanism causing them, strictures can be categorized as inflammatory, fibrotic, or mixed. Determining the relative amounts of inflammation and fibrosis in a stricture can influence treatment decisions. Imaging is an extremely useful tool in patients with small bowel stricturing CD to confirm the diagnosis and to evaluate disease characteristics, usually using CT or MRI. The aim of this paper is to describe how imaging can evaluate a patient with small bowel CD stricture.

Keywords