Pain Research and Management (Jan 2009)

Ultra Low-Dose Naloxone and Tramadol/Acetaminophen in Elderly Patients Undergoing Joint Replacement Surgery: A Pilot Study

  • Ngozi N Imasogie,
  • Sudha Singh,
  • James T Watson,
  • Debbie Hurley,
  • Patricia Morley-Forster

DOI
https://doi.org/10.1155/2009/497217
Journal volume & issue
Vol. 14, no. 2
pp. 103 – 108

Abstract

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OBJECTIVE: A pilot study was conducted to assess whether both the rationale and feasibility exist for future randomized clinical trials to evaluate the combined use of naloxone infusion and tramadol/acetaminophen as opioid-sparing drugs in elderly patients undergoing lower extremity joint replacement surgery.