Effect of age on some renal function tests, uric acid, and gamma glutamyl transferase (GGT) in sample of Iraqi men over 40 years

Abstract

Background: The prevalence of some aging markers that is part of metabolic syndrome elements are increasing worldwide, and the renal function is a major goal of this syndrome. Aim: To correlate the age with some renal function tests (blood urea and serum creatinine), serum uric acid (S.UA) and serum gamma glutamyl transferase (S.GGT).Material and methods: This study involve 127 men apparently healthy (≥ 40 years old) were analyzed for blood urea, serum creatinine, uric acid and gamma glutamyl transferase by the spectrophotometer methods by use the previously prepared kits from linear chemicals company.. Results: The mean age of men was (55.535±10.738)years. The men under study were divided into four groups according to age: 46 men (36.22%) their age range were ≥40 years, 33 cases (25.984%), 28 case (22.047%) and 20 others (15.748%) were (50-59), (60-69) and (≥70) years respectively. The mean ± Std. Deviation of variables in study were B. urea (42.387±3.682) mg/dl, S. creatinine (1.004±0.158) mg/dl, S.UA (6.216±0.829) mg/dl, and S.GGT (28.844±7.741) U/l. Older age was significantly associated with increased in B. urea and S. creatinine, while no significant association was found between age and S.UA and S.GGT in Iraqi men at (P ≤0.05 for all factors).Conclusions: older men are more liable to have higher B. urea and S. creatinine, with no relation between age and the levels of both uric acid and GGT in serum of Iraqi men under study.

Keywords

• age
• men
• renal function
• s.ua
• ggt