Grafting Dendrons onto Pillar[5]Arene Scaffolds

Abstract

With their ten peripheral substituents, pillar[5]arenes are attractive compact scaffolds for the construction of nanomaterials with a controlled number of functional groups distributed around the macrocyclic core. This review paper is focused on the functionalization of pillar[5]arene derivatives with small dendrons to generate dendrimer-like nanomaterials and bioactive compounds. Examples include non-viral gene vectors, bioactive glycoclusters, and liquid-crystalline materials.

Keywords

• pillar[5]arene
• dendrimers
• liquid crystals
• transfection
• glycoclusters