Molecules (Apr 2021)

Grafting Dendrons onto Pillar[5]Arene Scaffolds

  • Iwona Nierengarten,
  • Michel Holler,
  • Marine Rémy,
  • Uwe Hahn,
  • Aurélien Billot,
  • Robert Deschenaux,
  • Jean-François Nierengarten

DOI
https://doi.org/10.3390/molecules26082358
Journal volume & issue
Vol. 26, no. 8
p. 2358

Abstract

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With their ten peripheral substituents, pillar[5]arenes are attractive compact scaffolds for the construction of nanomaterials with a controlled number of functional groups distributed around the macrocyclic core. This review paper is focused on the functionalization of pillar[5]arene derivatives with small dendrons to generate dendrimer-like nanomaterials and bioactive compounds. Examples include non-viral gene vectors, bioactive glycoclusters, and liquid-crystalline materials.

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