Medicine (Jun 2022)

Malignant giant cell tumor of toe

  • Kazuhiko Hashimoto, MD,
  • Shunji Nishimura, MD,
  • Tomohiko Ito, MD,
  • Masao Akagi, MD,
  • , PhD

DOI
https://doi.org/10.1097/MD.0000000000029471
Journal volume & issue
Vol. 101, no. 22
p. e29471

Abstract

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Abstract. Introduction:. A giant cell tumor of soft tissue (GCST) is a benign soft tissue tumor that often occurs subcutaneously in the extremities. Rare cases of malignant GCST have been reported, but its pathogenesis remains unclear. Patients concerns:. We report a case of a 68-year-old man who noticed a painless mass on his second toe one and a half years ago. He visited the Department of Dermatology at our hospital. Magnetic resonance imaging revealed a soft tissue tumor, surrounding the distal aspect of the second toe. Diagnosis:. A biopsy of the tumor was performed by a dermatologist, and it revealed a malignant giant cell tumor of the toe. Interventions:. He was referred to our department and underwent lay amputation for wide-margin resection. Outcomes:. No recurrence or metastasis was observed 5 years after treatment. Conclusion. : Malignant GCST should be treated with wide-margin resection immediately after its diagnosis.