Effects of Clinical and Laboratory Findings on Prognosis of Patients with Acute Pancreatitis: Retrospective Evaluation

Abstract

Purpose: Acute pancreatitis(AP) is a disease that seen with abdominal pain and high serum amylase and lipase levels. Its mortality and morbidity are high. In this study, the demographic data, clinical and laboratory findings of patients hospitalized in our hospital with a diagnosis of AP were analyzed, and the effects of these findings on prognosis were investigated retrospectively. Materials and Methods: This study was conducted on 457 patients who were followed up with the AP diagnosis at our hospital's Internal Medicine and Emergency Medicine Clinic between January 2016 and January 2019. Results: Of the patients, 160 (35%) were male, 297 were female (65%), and the mean age was 57.7 (min:18-max:106). All of our patients who died were over 70 years old and had at least one comorbidity. There was no statistically significant difference between mild and severe AP patients in terms of gender, etiology, CRP, amylase, and hospitalization days. There was a strong significance in terms of age. The etiology of 369 (80.7%) of our patients originated from the gall bladder, and causes of 88 (19.3%) of them were not related to the gallbladder. The average Ranson score of the patients was 1.28. Conclusion: Considering that the severity of the disease increases significantly with age, we think that it is important to monitor elderly patients carefully and to be followed up in centers with intensive care units. Because of the different clinical characteristics of patients with AP, determining the clinical severity in the early period can provide an effective treatment approach and minimize the complications that may develop.

Keywords

• epidemiology
• etiology
• pancreatitis severity
• ranson