Nature Communications (Sep 2022)

Small, correlated changes in synaptic connectivity may facilitate rapid motor learning

  • Barbara Feulner,
  • Matthew G. Perich,
  • Raeed H. Chowdhury,
  • Lee E. Miller,
  • Juan A. Gallego,
  • Claudia Clopath

DOI
https://doi.org/10.1038/s41467-022-32646-w
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 14

Abstract

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How animals are able to rapidly adapt their behaviour to changing environmental demands remains poorly understood. Here, the authors use a modelling approach to show that synaptic plasticity in motor cortex may underlie rapid motor learning, demonstrating that small, correlated connectivity changes that preserve neural covariance are highly effective in driving behavioural adaptation.